News

Safety and efficacy of tamoxifen in boys with Duchenne muscular dystrophy (TAMDMD): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.

Henzi BC, Schmidt S, Nagy S, Rubino-Nacht D, Schaedelin S, Putananickal N, Stimpson G; North Star Consortium; Amthor H, Childs AM, Deconinck N, de Groot I, Horrocks I,...

25 Oktober 2023


Molecular control of endurance training adaptation in male mouse skeletal muscle.

Furrer R, Heim B, Schmid S, Dilbaz S, Adak V, Nordström KJV, Ritz D, Steurer SA, Walter J, Handschin C. Nat Metab. 2023 Sep 11.

23 Oktober 2023


In vitro-generated human muscle reserve cells are heterogeneous for Pax7 with distinct molecular states and metabolic profiles.

Bouche A, Borner B, Richard C, Grand Y, Hannouche D, Laumonier T. Stem Cell Res Ther. 2023 Sep 8;14(1):243

16 Oktober 2023


Identification of a muscle-specific isoform of VMA21 as a potent actor in X-linked myopathy with excessive autophagy pathogenesis.

Cocchiararo I, Cattaneo O, Rajendran J, Chabry F, Cornut M, Soldati H, Bigot A, Mamchaoui K, Gibertini S, Bouche A, Ham DJ, Laumonier T, Prola A, Castets P. Hum Mol...

11 Oktober 2023


Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9.

Thürkauf M, Lin S, Oliveri F, Grimm D, Platt RJ, Rüegg MA. Nat Commun. 2023 Sep 30;14(1):6116.

30 September 2023


Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns.

Pérez-Berlanga M, Wiersma VI, Zbinden A, De Vos L, Wagner U, Foglieni C, Mallona I, Betz KM, Cléry A, Weber J, Guo Z, Rigort R, de Rossi P, Manglunia R, Tantardini E,...

04 September 2023


SPTLC1 p.Leu38Arg, a novel mutation associated with childhood ALS.

Lone MA, Zeng S, Bourquin F, Wang M, Huang S, Lin Z, Tang B, Zhang R, Hornemann T. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Sep;1868(9):159359.

01 September 2023


Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells.

Qabrati X, Kim I, Ghosh A, Bundschuh N, Noé F, Palmer AS, Bar-Nur O. NPJ Regen Med. 2023 Aug 8;8(1):43.

08 August 2023


Guideline "Motor neuron diseases" of the German Society of Neurology (Deutsche Gesellschaft für Neurologie).

Petri S, Grehl T, Grosskreutz J, Hecht M, Hermann A, Jesse S, Lingor P, Löscher W, Maier A, Schoser B, Weber M, Ludolph AC. Neurol Res Pract. 2023 Jun 15;5(1):25.

15 Juni 2023


The mitochondrial calcium uniporter (MCU) activates mitochondrial respiration and enhances mobility by regulating mitochondrial redox state.

Weiser A, Hermant A, Bermont F, Sizzano F, Karaz S, Alvarez-Illera P, Santo-Domingo J, Sorrentino V, Feige JN, De Marchi U. Redox Biol. 2023 Jun 4;64:102759.

04 Juni 2023