News

Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation.

Moursy A, Allain FH, Cléry A. Nucleic Acids Res. 2014 Apr 1.

07 aprile 2014


Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1α.

Arnold AS, Gill J, Christe M, Ruiz R, McGuirk S, St-Pierre J, Tabares L, Handschin C. Nat Commun. 2014 Apr 1;5:3569.

02 aprile 2014


Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases.

Svensson K, Handschin C. Drug Discov Today. 2014 Mar 12. Review

19 marzo 2014


Molecular targets to treat muscular dystrophies.

Kinter J, Sinnreich M. Swiss Med Wkly. 2014 Feb 19.

24 febbraio 2014


Injection of a Soluble Fragment of Neural Agrin (NT-1654) Considerably Improves the Muscle Pathology Caused by the Disassembly of the Neuromuscular Junction.

Hettwer S, Lin S, Kucsera S, Haubitz M, Oliveri F, Fariello RG, Ruegg MA, Vrijbloed JW. PLoS One. 2014 Feb 10;9(2)

24 febbraio 2014


The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling.

Pérez-Schindler J, Summermatter S, Santos G, Zorzato F, Handschin C. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20314-9.

20 dicembre 2013


MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation.

Puttini S, van Zwieten RW, Saugy D, Lekka M, Hogger F, Ley D, Kulik AJ, Mermod N. BMC Mol Biol. 2013 Dec 2;14:26.

10 dicembre 2013


Functional crosstalk of PGC-1 coactivators and inflammation in skeletal muscle pathophysiology.

Eisele PS, Handschin C. Semin Immunopathol. 2013 Nov 21.

01 dicembre 2013


Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival.

Saxena S, Roselli F, Singh K, Leptien K, Julien JP, Gros-Louis F, Caroni P. Neuron. 2013 Oct 2;80(1):80-96.

15 ottobre 2013


Pharmacological prospects in the treatment of Duchenne muscular dystrophy.

Ruegg UT. Curr Opin Neurol. 2013 Oct;26(5):577-84.

01 ottobre 2013