News

Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models.

Harlan BA, Killoy KM, Pehar M, Liu L, Auwerx J, Vargas MR. Exp Neurol. 2020 Jan 31;327:113219

31 gennaio 2020


PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase.

D'Hulst G, Soro-Arnaiz I, Masschelein E, Veys K, Fitzgerald G, Smeuninx B, Kim S, Deldicque L, Blaauw B, Carmeliet P, Breen L, Koivunen P, Zhao SM, De Bock K. Nat...

18 gennaio 2020


Lifestyle vs. pharmacological interventions for healthy aging.

Furrer R, Handschin C. Aging (Albany NY). 2020 Jan 10:5-7.

07 gennaio 2020


Structural basis of a small molecule targeting RNA for a specific splicing correction.

Campagne S, Boigner S, Rüdisser S, Moursy A, Gillioz L, Knörlein A, Hall J, Ratni H, Cléry A, Allain FH. Nat Chem Biol. 2019 Dec;15(12):1191-1198

09 dicembre 2019


Neurologic complications of acute hepatitis E virus infection.

Ripellino P, Pasi E, Melli G, Staedler C, Fraga M, Moradpour D, Sahli R, Aubert V, Martinetti G, Bihl F, Bernasconi E, Terziroli Beretta-Piccoli B, Cerny A, Dalton HR,...

05 dicembre 2019


mTORC2 affects the maintenance of the muscle stem cell pool.

Rion N, Castets P, Lin S, Enderle L, Reinhard JR, Rüegg MA. Skelet Muscle. 2019 Dec 2;9(1):30.

02 dicembre 2019


Effect of Combination l-Citrulline and Metformin Treatment on Motor Function in Patients With Duchenne Muscular Dystrophy: A Randomized Clinical Trial.

Hafner P, Bonati U, Klein A, Rubino D, Gocheva V, Schmidt S, Schroeder J, Bernert G, Laugel V, Steinlin M, Capone A, Gloor M, Bieri O, Hemkens LG, Speich B, Zumbrunn T,...

13 novembre 2019


PGC-1α plays a pivotal role in simvastatin-induced exercise impairment in mice.

Panajatovic MV, Singh F, Roos NJ, Duthaler U, Handschin C, Krähenbühl S, Bouitbir J. Acta Physiol (Oxf). 2019 Oct 12.

12 ottobre 2019


Voluntary Resistance Running as a Model to Induce mTOR Activation in Mouse Skeletal Muscle.

D'Hulst G, Palmer AS, Masschelein E, Bar-Nur O, De Bock K. Front Physiol. 2019 Oct 4;10:1271.

04 ottobre 2019