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Les progrès de la recherche sont l'unique espoir pour les patients de trouver des thérapies efficaces!
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Soutenez la recherche dans le domaine des maladies génétiques rares!
Grant opportunity
We are inviting biomedical research proposals aimed at finding therapies for SMA or at elucidating the basic pathophysiological processes of the disease.
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Myology 2022 and mitoNice
Nice, France, 12-17 September 2022
A joint session in the afternoon of September 15th will ensure a smooth transition between the two congresses.
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Grant opportunity
MDF will prioritize funding at least one project focused on DM2 and will accept and consider proposals for both DM1 and DM2.
Deadline for submissions: September 9th
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New Directions Conference
Ft. Lauderdale, 20-23 June 2022
The biennial meeting is organized by H. Lee Sweeney and Elizabeth McNally. The conference will highlight current developments in muscle biology, disease, and therapy with presentations by leading international researchers.
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13th International Myotonic Dystrophy Consortium Meeting
Osaka, Japan, 21-25 June 2022
Hybrid format. An on-demand video recording of the meeting will be available for one month after the conference.
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International Conference on Muscle Wasting
Ascona, 11-16 September 2022
This meeting will focus on the intersection between basic aging mechanisms and their effect on skeletal muscle disease - particular focus will include cachexia, frailty and sarcopenia.
Abstracts until June 5th, registration until August 28th
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The 27th International Annual Congress of the World Muscle Society
Halifax, 11-15 October 2022 (hybrid)
The main thematic topics this year are: new developments in congenital muscle disease, neuropathies and non-5q motor neuron disease, the development of therapeutic approaches.
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Early Career Programme
Interested in participating in one of the upcoming ENMC workshops? If you are a young scientist (up to 5 years from your PhD defense) you may be eligible for a free participation.
List of upcoming ENMC workshops
Young Scientists Programme, conditions and guidelines
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New papers
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Integrative molecular roadmap for direct conversion of fibroblasts into myocytes and myogenic progenitor cells.
Kim I, Ghosh A, Bundschuh N, Hinte L, Petrosyan E, von Meyenn F, Bar-Nur O.
Sci Adv. 2022 Apr 8;8(14):eabj4928.
08 avril 2022
Skeletal Muscle Disorders: A Non-cardiac Source of Cardiac Troponin T.
du Fay de Lavallaz J, Prepoudis A, Wendebourg MJ, Kesenheimer E, Kyburz D, Daikeler T, Haaf P, Wanschitz J, Löscher WN, Schreiner B, Katan M, Jung HH, Maurer B, Hammerer-Lercher A, Mayr A, Gualandro...
07 avril 2022
Creatine transporter-deficient rat model shows motor dysfunction, cerebellar alterations, and muscle creatine deficiency without muscle atrophy.
Duran-Trio L, Fernandes-Pires G, Grosse J, Soro-Arnaiz I, Roux-Petronelli C, Binz PA, De Bock K, Cudalbu C, Sandi C, Braissant O.
J Inherit Metab Dis. 2022 Mar;45(2):278-291.
31 mars 2022
Evaluation of real-life outcome data of patients with spinal muscular atrophy treated with nusinersen in Switzerland.
Tscherter A, Rüsch CT, Baumann D, Enzmann C, Hasselmann O, Jacquier D, Jung HH, Kruijshaar ME, Kuehni CE, Neuwirth C, Stettner GM, Klein A; Swiss-Reg-NMD group.
Neuromuscul Disord. 2022 Feb...
25 mars 2022
Myostatin gene inactivation increases post-mortem calpain-dependent muscle proteolysis in mice.
Nassar R, Vernus B, Carnac G, Fouret G, Goustard B, Casas F, Tintignac L, Cassar-Malek I, Picard B, Seiliez I, Brioche T, Koechlin-Ramonatxo C, Bertrand-Gaday C, Hamade A, Najjar F, Chabi B, Bonnieu...
15 mars 2022
Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors.
Ruiz A, Benucci S, Duthaler U, Bachmann C, Franchini M, Noreen F, Pietrangelo L, Protasi F, Treves S, Zorzato F.
Elife. 2022 Mar 3;11:e73718.
03 mars 2022
Enforced tethering elongates the cortical endoplasmic reticulum and limits store-operated calcium entry.
Henry C, Carreras-Sureda A, Demaurex N.
J Cell Sci. 2022 Feb 22:jcs.259313.
22 février 2022
Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy.
Laurila PP, Luan P, Wohlwend M, Zanou N, Crisol B, Imamura de Lima T, Goeminne LJE, Gallart-Ayala H, Shong M, Ivanisevic J, Place N, Auwerx J. Sci Adv. 2022 Jan 28;8(4):eabh4423.
28 janvier 2022
GCN5 maintains muscle integrity by acetylating YY1 to promote dystrophin expression.
Addicks GC, Zhang H, Ryu D, Vasam G, Green AE, Marshall PL, Patel S, Kang BE, Kim D, Katsyuba E, Williams EG, Renaud JM, Auwerx J, Menzies KJ.
J Cell Biol. 2022 Feb 7;221(2):e202104022.
14 janvier 2022
Creatine transporter-deficient rat model shows motor dysfunction, cerebellar alterations, and muscle creatine deficiency without muscle atrophy.
Duran-Trio L, Fernandes-Pires G, Grosse J, Soro-Arnaiz I, Roux-Petronelli C, Binz PA, De Bock K, Cudalbu C, Sandi C, Braissant O.
J Inherit Metab Dis. 2021 Dec 22.
22 décembre 2021