Swiss scientists network

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Last update: January 2024


Lab Prof. Hugues Abriel

Institute of Biochemistry and Molecular Medicine, University of Bern

Institute infrastructure: Cell culture and microscopy techniques, electrophysiology (conventional), protein interaction techniques
Animal models: TRPM4 KO and KI animals.

TeamPersonal expertise
Prof. Hugues AbrielChannelopathies, ion channels and protein-protein interactions 

Dr. Jean-Sébastien Rougier
senior scientist

Cell culture, patch-clamp (heterologous expression system, iPSC, and cardiomyocytes), newborn cardiomyocytes isolation, molecular cloning, protein-protein proximity assay, immunostaining.
Sabrina Guichard
Cardiomyocytes isolation, genotyping, molecular cloning, generation transgenic animal, co-immunoprecipitation, western blot, biotinylation, immunostaining, patch clamp HEK-293.
Anne-Flore Hämmerli
Patch-clamp, atrial cardiomyocytes isolation, 
Dr. Oksana Iamshanova
Patch clamp HEK-293, co-immunoprecipitation, western blot, biotinylation
Dr. Patricia Teixidor
scientific officer
Nada Elmakhzen
PhD student
Lipsa Panda
PhD student
Dominic Schneiter 
PhD Student
Michele Fuhrer 
MD Student


Lab Prof. Frédéric Allain

Institute of Biochemistry, ETH Zürich

Institute infrastructure: Determination of structures at atomic resolution of Protein-RNA and drug-RNA complexes using Nuclear Magnetic Resonance spectroscopy (NMR)

TeamPersonal expertise
Prof. Frédéric AllainNMR, ITC, splicing assay
Dr. Antoine Cléry
senior scientist
NMR, ITC, splicing assay 


Lab Prof. Francesca Amati

Aging and Muscle Metabolism lab, Department of Physiology & Institute of Sport Sciences, University of Lausanne

Lab infrastructure: Human physiology and metabolism research lab including exercise testing, exercise intervention, stable isotope tracers, glucose clamps, indirect calorimetry, body composition.
Zebrafish facility, breeding, exercise testing and training.
Primary muscle cell cultures, respirometry, mitochondria isolation, wet lab, microsopy

TeamPersonal expertise
Prof. Francesca AmatiClinical and translational research in muscle metabolism and aging, including muscle wasting, sarcopenia, insulin resistance and the development of other chronic diseases related to muscle metabolism. Our lab research projects include specific subcellular compartments, organelle dynamics and contact sites (mitochondria, lipid droplets, etc).
Dr. Sylviane Lagarrigue
Mitochondrial metabolism, respirometry (Seahorse XF analyzers), primary cell cultures
Dogan Grepper
PhD student
Zebrafish models
Cassandra Tabasso
PhD student
Dr. Ammar Ebrahimi
Small molecules and peptides, Drosophila models
Axel Aguettaz
PhD student
Imaging (high resolution, confocal, electron microscopy) 


Lab Prof. Johan Auwerx

Laboratory of Integrative and Systems Physiology (LISP) – Ecole Polytechnique Fédérale de Lausanne (EPFL)

Lab infrastructure: 
Goals: to understand the role of mitochondria and proteostasis in health, disease, and aging
Strategy: systems & population genetics, molecular & cellular biology, and computational approaches
Model systems: C. elegans, mouse genetic reference populations, humans
Keywords: Metabolic sensing, Mitochondrial metabolism, Nuclear receptor and cofactor biology, Complex genetics, Genetic reference populations, Aging

TeamPersonal expertise
Prof. Johan AuwerxMetabolism, Aging, muscle wasting, sarcopenia, Duchenne Muscular Dystrophy, IBM, mouse and human genetics, NAD biology, mitochondria.    
Ioanna Daskalaki
Muscle stem cell, Duchenne Muscular Dystrophy, mitochondria and metabolism
Yasmine Liu
Muscle stem cell, Duchenne Muscular Dystrophy, mitochondria and metabolism
Amelia Lalou
PhD student
Aging, proteostasis, mitochondria.


Lab Prof. Ori Bar-Nur

Regenerative and Movement Biology lab, Department of Health Sciences and Technology, ETH Zurich

Lab infrastructure and techniques
I) Tissue culture: primary muscle cell culture, pluripotent stem cell culture (mouse, rat, human), reprogramming somatic cells into induced pluripotent stem cells (mouse, rat, human), reprogramming somatic cells into myogenic progenitors (mouse), isolation of fibro-adipogenic progenitors and satellite cells using surface markers, intramuscular cell transplantation and graft analysis.
(II) Relevant mouse strains:  C57BL/10ScSn-Dmdmdx/J, B10ScSn.Cg-Prkdcscid Dmdmdx/J, B6.Cg-Pax7tm1(cre/ERT2)Gaka/J, Pax7-nGFP. 

TeamPersonal expertise
Prof. Ori Bar-NurStem cell biology with emphasis on pluripotent and satellite stem cells, direct lineage reprogramming methods such as 
conversion of somatic cells into muscle cells, principles of skeletal muscle regeneration. 
Nicola Bundschuh
Lab manager
Primary muscle cell culture, reprogramming somatic cells into induced pluripotent stem cells, 
genome editing using CRISPR-Cas9, flow cytometry, FACS sorting.

Giada Bacchin
PhD student

Direct reprogramming of somatic cells into myogenic progenitors, primary muscle/fibroblast cell culture and isolation, 
production of viral vectors, molecular cloning, human iPSCs, flow cytometry, biomaterials.
Veerle de Goederen
PhD student
Muscle cell dedifferentiation, fish cell culture, transcriptomics
Christine Trautmann
PhD student
Primary muscle cell isolation and cell culture of bovine myoblasts and muscle fibers
Ajda Lenardic
PhD student
Gene editing and genetic engineering,  cell biology with the focus on reprogramming of somatic cells into induced pluripotent stem cells and myogenic cells
Pjeter Gjonlleshaj
PhD student
stem cell biology
Ali Kerem Kalkan
PhD student
Human iPSCs and primary muscle cell culture, reprogramming human somatic cells into iPSCs, 3D muscle differentiation, 
Golden Gate cloning, transcriptional regulation using CRISPR-Cas nucleases, FACS sorting.


Lab. Prof. Perrine Castets

University of Geneva, Faculty of Medicine, Department Cell Physiology and Metabolism

Institute infrastructure: Microscopy, FACS, genomic platform, Proteomics facility, cell culture, muscle electroporation, AAV

TeamPersonal expertise
Prof. Perrine Castets
SNSF Assistant Professor
Muscle physiology; molecular biology; transgenic animal models; neuromuscular diseases; neuromuscular junction; autophagy
Dr. Alexandre Prola
Maître Assistant
Molecular biology; metabolism; Muscle Stem Cells; mitochondria; Ca2+ flux
Florent Chabry TechnicienMouse genotyping; immunohistochemistry; Signaling Pathway analysis
Loris Levet
PhD student
Molecular biology; autophagy; autophagic vacuolar myopathies, histology
Ilaria Cocchiararo
PhD student
Molecular biology; autophagy; autophagic vacuolar myopathies, histology


Lab Prof. Katrien De Bock

Exercise and Health lab, Department of Health Sciences and Technology, ETH Zurich

Lab infrastructure and techniques: (I) Freshly isolated cell culture: primary muscle cell culture, isolation of satellite cells, fibro-adipogenic progenitors, immune cells and muscle endothelial cells, (II) Muscle physiology and regeneration in vivo: intramuscular cell transplantation and graft analysis, skeletal muscle injury: cardiotoxin, glycerol and hind-limb ischemia, TSE running wheel system, indirect calorimetry analysis (Sable systems metabolic cages). (III) Relevant mouse strains:  Pax7-mTmG. Mouse lines to study vascular biology in muscle.

TeamPersonal expertise
Prof. Katrien De BockMetabolic reprogramming and crosstalk during muscle regeneration, exercise physiology, cell-cell interactions in skeletal muscle.

Dr. Inés Soro-Arnáiz

Satellite cell isolation and culture, cardiotoxin-induced muscle injury, intramuscular satellite cell transplantation, immunofluorescent imaging and analysis of muscle tissue, flow cytometry


Lab Prof. Tobias Derfuss

University of Basel and University Hospital Basel

Lab infrastructure and techniques: Acetlycholine Receptor-specific, human-derived, monoclonal antibodies

TeamPersonal expertise

Dr. Nicholas Sanderson
group leader


Sebstian Holdermann
PhD student


Lab Prof. Maud Frieden

University of Geneva, Department of Cell Physiology and Metabolism

Institute infrastructure: Calcium imaging, electrophysiology, human primary cell culture, lentivirus

TeamPersonal expertise
Prof. Maud FriedenMyogenesis and muscle regeneration, electrophysiology, Ca2+ imaging
Dr. Stephane Koenig
scientific collaborator
Reserve cell activation, molecular biology, myogenesis and muscle regeneration, lentivirus, signal transduction
Dr. Tahir Idris
Extracellular matrix, molecular biology, myotube maturation, signal transduction
Loann Laubry
PhD student
Myoblast differentiation, Signal transduction, Ca2+ imaging, electrical stimulation on cell culture
Mélanie Fourgeaud
PhD student
Reserve cell activation, genomic data analysis, molecular biology, signal transduction
Olivier Dupont
Lab technician
Myoblast differentiation, Signal transduction, Ca2+ imaging


Lab Prof. Christoph Handschin

Biozentrum, University of Basel

Institute infrastructure: Treadmill (open and closed), voluntary wheel running, grip strength, CLAMS (comprehensive laboratory animal monitoring system), qNMR (body composition)

TeamPersonal expertise
Prof. Christoph HandschinSkeletal muscle cell plasticity in health and disease incl. exercise and muscle wasting pathologies
Dr. Regula Furrer

Dysferlinopathy (in vivo testing, in situ force measurements


Lab Prof. Marisa Jaconi

University of Geneva, Faculty of Medicine, Department of Basic Neurosciences 

Institute infrastructure: Cell culture and microscopy techniques; pre-GMP and GMP lab; muscle physiology; animal facility and analysis of muscle function

TeamPersonal expertise
Prof. Marisa JaconiHuman pluripotent stem cells (ESC and iPSC) and tissue-derived stem cells 
Cardiac and skeletal muscle differentiation
Organoids and tissue engineering
Cell therapy strategies and GMP cell production
Setup for 3D sound-induced morphogenesis (Cymatix)
Setups for microfluidics and electrophysiological characterization of organoids 

Dr. Tania Rodrigues 

Mesoangioblast biology, muscle differentiation and functional analysis, lentivector transduction and clonal selection
GMP isolation and cell banking 
Martha Iabel Gonzalez Duque
Stem cells and cardiac valve reconstruction, 3D bioprinting, sound-induced morphogenesis


Lab Alexis Jourdain

Mitochondria & Energy Metabolism lab, Department of Biochemistry, University of Lausanne

Lab infrastructure and techniques:  (I) Tissue culture: muscle, cancer and immune cell culture. (II) Systems biology: genome-wide CRISPR/Cas9 screening, nutrient screening, omics. (III) Mitochondrial biology: Respirometry, mtDNA expression, respiratory chain complexes assembly, mitochondrial disorders.

TeamPersonal expertise
Prof. Alexis Jourdain
Mitochondria, systems biology
Sylvain Chollet
biologist/lab manager
Emeline Recazens
Mitochondria, muscle cell differentiation
Miriam Lisci
Mitochondria, T cell immunometabolism
Mads Møller Foged
Joan Blanco Fernandez
PhD student
Mitochondria, macrophage immunometabolism
Abigail Lee Strefeler
PhD student
Mitochondria, nutrient metabolismy
Marcell Harhai
PhD student


Lab Prof. Didier Hannouche & Dr. Thomas Laumonier

Department of Orthopaedic Surgery, Faculty of Medicine & University Hospital, Geneva, Switzerland

Institute infrastructure: Hypoxic chamber, Whole Animal System for muscle physiology testing in mice, bioluminescence imaging.

TeamPersonal expertise
Dr. Thomas Laumonier
Senior scientist, PhD
Co-responsible of the lab
Isolation of human myogenic stem cells, cell therapy, immunology, flow cytometry, gene therapy, bioluminescence imaging
Prof. Didier Hannouche
Professor, MD
Co-responsible of the lab
Orthopaedic surgery, cell therapy
Dr. Laure Gallay
Animal microsurgery, PCR, histology
Axelle Bouche
PhD student
Cell culture, flow cytometry, cell transplantation
Diego Michel
Master student
Cell culture, flow cytometry, immunofluorescence

Dr. Axel Tollance

Primary human cell culture, Flow cytometry, Seahorse


Lab Prof. Robert Katzschmann

Departement für Maschinenbau und Verfahrenstechnik, CLA Building, Laboratory of Soft Robotics, ETH Zurich

Institute infrastructure: 3D extrusion bioprinter, 3D printers, equipment for electrical stimulation of muscle cells and tissue

TeamPersonal expertise
Robert Katzschmann
Assistant Professor
Soft Robotics, Mechanical Engineering, Muscle Tissue Engineering, Electrical Stimulation of Muscle Cells and Tissue, Bio-hybrid Robots

Miriam Filippi
Senior scientist

Muscle Tissue Engineering, Electrical Stimulation of Muscle Cells and Tissue, Biofabrication, 3D Extrusion Bioprinting, Bio-hybrid Robots
Oncay Yasa
Soft Robotics, Mechanical Engineering, Muscle Tissue Engineering, Electrical Stimulation of Muscle Cells and Tissue, 3D Extrusion Bioprinting, Biomaterials, Bio-hybrid Robots
Lewis Jones
PhD student
Cardiac and Skeletal Muscle Tissue Engineering, Volumetric 3D Bioprinting, Bio-hybrid Robots
Aiste Balciunaite
PhD student
Asia Badolato
PhD student
Manuel Mekkattu
PhD student


Lab Prof. Peter Meister

Institute of Cell Bioogy, University of Bern

Institute infrastructure: Confocal Microscopy, Spinning Disk microscopy 

TeamPersonal expertise
P.D. Peter MeisterC. elegans, muscle differentiation, epigenetics, nuclear organization, microscopy
Karthik Mohanraj
Cell plasticity, muscle cell induction, pluripotency, genetic screens


Lab Prof. Nicolas Mermod

University of Lausanne, Biotechnology

Institute infrastructureMuscle in situ electroporation, integrating and non-integrating non-viral DNA expression vectors, Next-generation DNA sequencing and genomics

TeamPersonal expertise
Nicolas Mermod
Gene  expression  and regulation, genomics, epigenetic regulatory elements, non-viral vectors
Dr. Lionel Mavoungou
Postdoctoral researcher
gene transfer in cultured muscle progenitor cells and transplantation, MDX murine model of Duchenne Muscular Dystrophy


Lab Prof. Matteo Moretti and Prof. Simone Bersini

Regenerative Medicine Technologies Lab, Ente Ospedaliero Cantonale (EOC), Bellinzona 
Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano

Institute infrastructure
Human cell culture, in vitro modelling, biofabrication, organs-on-a-chip

  • Isolation and culture of primary cells from human musculo-skeletal biopsies (e.g. myoblasts, fibroblasts, mesenchymal stem cells)
  • Biofabrication of miniaturized in vitro models of the human skeletal muscle microenvironment embedding muscle fibers, endothelial cells and muscle-specific stromal cells
  • Biofabrication of human microvascular networks with applications in musculo-skeletal pathologies, oncology and aging

Technologies and techniques: Fused-deposition modelling 3D printer, Digital light processing 3D printer, Volumetric 3D bioprinter, Laser cutter, Plasma cleaner, High-vacuum pumps, Nitrogen gas generator, Nitrogen oven, Soft lithography, Electrical stimulation, Microfabrication, Microfluidics and organs-on-a-chip, Automated liquid handling, Confocal high-content imaging system, Biofabrication and Hydrogel patterning, Computational fluid dynamic simulations

TeamPersonal expertise
Prof. Matteo MorettiTissue engineering, regenerative medicine for musculo-skeletal tissues (e.g. bone, muscle, cartilage, tendons), bioreactors, 3D printing
Prof. Simone BersiniMuscle biofabrication, organ-specific vascularization, microfluidics, organs-on-a-chip for modeling cancer metastases and human aging
Stella Monestier
PhD student
Bioprinting, microphysiological systems
Megi Ishmaku
Research assistant
Primary cell isolation and culture, microfabrication
Giuseppe Talò
Design of electro-mechanical systems, computer-aided design, microfabrication, 3D printing, bioprinting
Marco Francese
Master student
Computer-aided design, computational fluid dynamic simulations, microfabrication



Lab Prof. Markus A. Rüegg

University of Basel, Biozentrum

Institute infrastructure: AAV technology; mouse models; muscle force measurement; microscopy; Proteomics and RNA-seq analysis; FACS analysis; voluntary wheel running; CRISPR/Cas9

TeamPersonal expertise
Markus A. Rüegg
Muscle physiology; molecular biology; transgenic animal models; neuromuscular diseases
Dr. Shuo Lin
Research associate
Development of neuromuscular junctions; muscle growth and muscular dystrophies
Dr. Judith Reinhard
Research associate
Molecular biology; biochemistry; histology; histochemistry; transgenic animal models; AAV-mediated gene therapy; muscular dystrophies (LAMA2 MD)
Dr. Daniel J. Ham
Research associate
Muscle physiology; sarcopenia; muscle function testing
Dr. Ines Böhm
Mammalian neuromuscular junctions, sarcopenia, cancer cachexia, method development, spatial transcriptomics, immunofluorescence, FDM 3D printing, microscopy + fluidics imaging, clinical trials (GCP), image analysis
Dr. Eleonora Maino
Molecular biology, genome editing, disease modelling, neuromuscular disorders
Dr. Marco Thürkauf
Molecular biology, muscle physiology, CRISPR/Cas9 technology, AAV preparation, omics data analysis
Dr. Alexander Ham
Molecular biology, muscle physiology, NMJ physiology, sn/scRNAseq technology, omics data analysis
Timothy McGowan
PhD student
Stem cells, muscle regeneration; muscular dystrophies (LAMA2 MD)
Julia Schedel
PhD student
Myotendinous junction, muscular dystrophies (LAMA2 MD), molecular biology
Alexia Böck Pereda
PhD student
Muscle biology, muscular dystrophies, molecular biology
Lena Jörin
Genotyping of mice, lab management
Nicolas Lewerenz
Master student
Primary myoblast culture, LAMA2 MD, AAV-mediated CRISPR/Cas9 delivery


Lab Dr. Francesco Santini and Prof. Oliver Bieri

Division of Radiological Physics, Department of Radiology, University Hospital Basel

Institute infrastructure: 1.5T and 3T human MRI scanners for in vivo imaging and spectroscopy, electronics laboratory, access to 31P coils for in vivo human spectroscopy and MR-compatible ergometer, equipment for electrical muscle stimulation during MRI.

TeamPersonal expertise
Prof. Oliver Bieri
Head of Radiological Physics
Methodological development, novel contrast mechanisms.
Dr. Francesco Santini
Head of Muscle MRI
Methodological development, dynamic  MRI; MRI safety; electronics design and development.
Dr. Xeni Deligianni
Methodological development, quantitative and dynamic MR imaging and spectroscopy; MR image and data analysis.
Dr. Claudia Weidensteiner
Methodological development, study design and data analysis, pediatric imaging.

Dr. Jakob Wasserthal

Image analysis and Artificial Intelligence
Tanja Haas
MRI scanning
Philipp Madörin
MRI scanning



Lab Prof. Smita Saxena

University of Bern, Dept. for Biomedical research and Dept. of Neurology, Insespital

Institute infrastructure: Confocal microscopy, spinning disk microscopy for live and calcium imaging, muscle force measurement, cell culture, voluntary wheel running, rotarod, stereotaxic surgery, optogenetics, laser dissection microscopy, ALS rodent models (SOD1, TDP-43 and C9ORF72).

TeamPersonal expertise
Smita Saxena
Degeneration of motor neruons and neuromuscular junctions in ALS, muscle factors that influence axonal regeneration status, mTOR signalling in motor neurons
Niran Maharjan
Senior Researcher
Motor neuron and iPSC-derived neuronal cultures, electron microscopy
Mert Dumansleep measurements
Federica Pilotto
PhD student
Carla Pernaci
PhD student
Rim Diab
PhD student

Alexander Schmitz
MD-PhD student



Lab Prof. Leonardo Scapozza

University of Geneva, Pharmaceutical Biochemistry

Institute infrastructure: Setup for measuring isometric force in sedated living mice or rats; Setup for measuring isometric and eccentric force in excised muscle; Setup for fluorescent imaging in living cells, mdx5Cv dystrophic mouse, mdx5Cv mice bearing conditional mutations for aromatase, estrogen receptors alpha and beta, cell culture facilities (P2 level), HTP plate readers, genomics platforms with capacity for RNA-sequencing and qPCR

TeamPersonal expertise
Prof. Leonardo ScapozzaBiophysics of interactions: ITC, SPR, Thermophoresis, Enzymology
Medicinal Chemistry: Cpds synthesis
Biochemistry: protein expression (mg scale), protein purification, target-based in vitro assay, protein characterization (SEC, SEC-MALS)
Dr. Olivier Dorchies
Senior Research Associate
Primary cultures of mouse skeletal muscle, in vivo force measurements, in vivo motor function (spontaneous locomotor activity, grid test, wheel running), Mouse models: mdx5Cv, FU-5Cv (muscle-specific, Dox-inducible, Flox-Utrophin mdx5Cv mouse), D2/5Cv (similar to D2.mdx, mdx5Cv allele in DBA/2J background). Influxes of radioactive calcium and sodium, fluorescent detection of ROS, roles of ROS and estrogen receptors in muscle dystrophy 
Dr. Hesham Ismail
Senior scientist
In vivo/ex vivo force measurements, primary mouse skeletal muscle cultures,  fluorescent imaging of intracellular pH, sodium fluxes, calcium fluxes, ROS, roles of ROS in muscle dystrophy
Dr. Laurence Neff
Research associate
Molecular biology, genome editing, viral vectors
Ghali Guedira
PhD student
In vivo/Ex vivo force measurements, roles of ROS in muscle dystrophy.


Lab Profs. Michael Sinnreich, Susan Treves and Francesco Zorzato

University of Basel, Department Neurologie & Biomedizin

Institute infrastructure: Translational research on muscular dystrophies, Congenital myopathies with special focus on excitation contraction coupling dysregulation and calcium homeostasis.

TeamPersonal expertise
Prof. Michael Sinnreich

Neuromuscular diseases
Muscular Dystrophies

Prof. Susan TrevesIntracellular calcium measurements, resting membrane potential measurements with fluorescent dyes, Preparation of primary muscle moytube cultures (human, mouse, EOM) Western blots, preparation of poly and monoclonal  Abs, protein purification
Prof. Francesco ZorzatoForce measurements on fast and slow twitch muscles, Ca2+ imaging on single muscle fibers, single fiber dissection, SPARK analysis, electroporation. Western blots, preparation of Abs, protein purification
Dr. Jochen Kinter
Experience in NGS, drug screenings, aptamers
Dr. Lionel Tintignac
senior scientist
Myogenesis, primary culture of muscle cells, NGS and Ribo-seq, proteomics and PTM. Proximity labeling
Dr. Christian Klingler
Experience in NGS, drug screenings, aptamers
Dr. Alexis Ruiz
Force measurements on fast and slow twitch muscles. Single fiber dissection and Ca2+ imaging on single muscle fibers. Confocal microscopy, Western blots, qPCR. In vivo assessment of mouse muscle force
Sofia Benucci
PhD student
Force measurements on fast, slow twitch muscles and EOM muscles. Histology of muscle sections. Ca2+ imaging on single muscle fibers and single cells, qPCR, confocal microscopy, western blotting. In vivo assessment of mouse muscle force
Yusuf Ertuna
Myogenesis, primary culture of muscle cells, proteomic and PTM. Proximity labeling

Huiying Li
PhD student

FACS sorting, cytokine profiling, EBV cells, immunocharacterisation
Wen Jin
MD, PhD student
Characterisation cell lines from patients carrying RyR1 mutations
Kenshiro Kido
Malignat Hyperthermia myotubes
Iren Cerem
Master student
EBV cells characterisation
Hervé Meier
Research Assistant (Master’s)
Western blots, qPCR, protein purification, cell and tissue culture, subcellular fractionation, calcium imaging and confocal 
Microscopy, pPCR and Western blotting
Raphael Schmid
Master Student
DUX4 Biogenesis, Ubiquitination, Protein Homeostatis
Adeline Stiefvater
Research technician
Mouse muscle dissection, primary muscle cell and fiber culture, drug screening. EX vivo myotonia measurements


Lab Prof. Patrick Tschopp

Laboratory of Regulatory Evolution, DUW Zoology, University of Basel

Institute infrastructure and techniques: (I) single-cell genomics: in-house production and bioinformatics analyses of single-cell genomics data sets, namely 10x Genomics scRNA-seq, snRNA-seq and scATAC-seq, as well as SMART-seq2 scRNA-seq (II) lightsheet microscopy: whole-mount immunohistochemistry, lightsheet microscopy and image analysis (III) Axonal backfills: muscle-specific axonal backfills and single-cell motor neuron picking in developing chicken embryos

TeamPersonal expertise
Prof. Patrick Tschopp
Developmental biology and evolutionary-comparative developmental biology, transcriptional regulation, functional genomics and single-cell functional genomics, experimental embryology
Dr. Maëva Luxey
Senior Research Associate
Developmental neurobiology, primary cell culture, axon guidance, axonal backfilling, muscle microdissection, functional genomics and single cell functional genomics, lightsheet and confocal microscopy, experimental embryology
Fabio Sacher
PhD student
Analysis of 10X and SMART-seq2 scRNA-seq data, DE testing, and data visualisation in R.    


Lab Dr. Bernhard Wehrle-Haller

University of Geneva, School of medicine

Institute infrastructure: Microscopy, live-cell imaging, cell culture, fluorescent proteins

TeamPersonal expertise
Dr. Bernhard Wehrle-Haller
Dynamic regulation of cell-matrix adhesions, live cell imaging, cell culture, FRAP, microscopy, live imaging
Michael Bachmann
Fluorescent tag-proteins, live imaging, FRAP, integrin signaling, surface patterning
Jérémy Kessler
PhD student


Lab Prof. Werner Z'Graggen

Inselspital Bern, Department of Neurology

Institute infrastructure: equipment for muscle and nerve excitability measurements, ENMG equipment, muscle MR imaging, histology, mitochondrial activity essays


TeamPersonal expertise
Prof. Hugh Bostock
PhD, researcher
Musle and nerve excitability measurements
Belén Rodriguez
Muscle and nerve excitability measurements