Swiss scientists network

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Last update: January 2024

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Lab Prof. Hugues Abriel

Institute of Biochemistry and Molecular Medicine, University of Bern

Institute infrastructure: Cell culture and microscopy techniques, electrophysiology (conventional), protein interaction techniques
Animal models: TRPM4 KO and KI animals.

Team	Personal expertise
Prof. Hugues Abriel	Channelopathies, ion channels and protein-protein interactions
Dr. Jean-Sébastien Rougier senior scientist	Cell culture, patch-clamp (heterologous expression system, iPSC, and cardiomyocytes), newborn cardiomyocytes isolation, molecular cloning, protein-protein proximity assay, immunostaining.
Sabrina Guichard technician	Cardiomyocytes isolation, genotyping, molecular cloning, generation transgenic animal, co-immunoprecipitation, western blot, biotinylation, immunostaining, patch clamp HEK-293.
Anne-Flore Hämmerli technician	Patch-clamp, atrial cardiomyocytes isolation,
Dr. Oksana Iamshanova Postdoc	Patch clamp HEK-293, co-immunoprecipitation, western blot, biotinylation
Dr. Patricia Teixidor scientific officer
Nada Elmakhzen PhD student
Lipsa Panda PhD student
Dominic Schneiter PhD Student
Michele Fuhrer MD Student

Lab Prof. Frédéric Allain

Institute of Biochemistry, ETH Zürich

Institute infrastructure: Determination of structures at atomic resolution of Protein-RNA and drug-RNA complexes using Nuclear Magnetic Resonance spectroscopy (NMR)

Team	Personal expertise
Prof. Frédéric Allain	NMR, ITC, splicing assay
Dr. Antoine Cléry senior scientist	NMR, ITC, splicing assay

Lab Prof. Francesca Amati

Aging and Muscle Metabolism lab, Department of Physiology & Institute of Sport Sciences, University of Lausanne

Lab infrastructure: Human physiology and metabolism research lab including exercise testing, exercise intervention, stable isotope tracers, glucose clamps, indirect calorimetry, body composition.
Zebrafish facility, breeding, exercise testing and training.
Primary muscle cell cultures, respirometry, mitochondria isolation, wet lab, microsopy

Team	Personal expertise
Prof. Francesca Amati	Clinical and translational research in muscle metabolism and aging, including muscle wasting, sarcopenia, insulin resistance and the development of other chronic diseases related to muscle metabolism. Our lab research projects include specific subcellular compartments, organelle dynamics and contact sites (mitochondria, lipid droplets, etc).
Dr. Sylviane Lagarrigue Postdoc	Mitochondrial metabolism, respirometry (Seahorse XF analyzers), primary cell cultures
Dogan Grepper PhD student	Zebrafish models
Cassandra Tabasso PhD student	Lipidomics
Dr. Ammar Ebrahimi PostDoc	Small molecules and peptides, Drosophila models
Axel Aguettaz PhD student	Imaging (high resolution, confocal, electron microscopy)

Lab Prof. Johan Auwerx

Laboratory of Integrative and Systems Physiology (LISP) – Ecole Polytechnique Fédérale de Lausanne (EPFL)

Lab infrastructure:
Goals: to understand the role of mitochondria and proteostasis in health, disease, and aging
Strategy: systems & population genetics, molecular & cellular biology, and computational approaches
Model systems: C. elegans, mouse genetic reference populations, humans
Keywords: Metabolic sensing, Mitochondrial metabolism, Nuclear receptor and cofactor biology, Complex genetics, Genetic reference populations, Aging

Team	Personal expertise
Prof. Johan Auwerx	Metabolism, Aging, muscle wasting, sarcopenia, Duchenne Muscular Dystrophy, IBM, mouse and human genetics, NAD biology, mitochondria.
Ioanna Daskalaki Post-Doc	Muscle stem cell, Duchenne Muscular Dystrophy, mitochondria and metabolism
Yasmine Liu Post-Doc	Muscle stem cell, Duchenne Muscular Dystrophy, mitochondria and metabolism
Amelia Lalou PhD student	Aging, proteostasis, mitochondria.

Lab Prof. Ori Bar-Nur

Regenerative and Movement Biology lab, Department of Health Sciences and Technology, ETH Zurich

Lab infrastructure and techniques:
I) Tissue culture: primary muscle cell culture, pluripotent stem cell culture (mouse, rat, human), reprogramming somatic cells into induced pluripotent stem cells (mouse, rat, human), reprogramming somatic cells into myogenic progenitors (mouse), isolation of fibro-adipogenic progenitors and satellite cells using surface markers, intramuscular cell transplantation and graft analysis.
(II) Relevant mouse strains: C57BL/10ScSn-Dmdmdx/J, B10ScSn.Cg-Prkdcscid Dmdmdx/J, B6.Cg-Pax7tm1(cre/ERT2)Gaka/J, Pax7-nGFP.

Team	Personal expertise
Prof. Ori Bar-Nur	Stem cell biology with emphasis on pluripotent and satellite stem cells, direct lineage reprogramming methods such as conversion of somatic cells into muscle cells, principles of skeletal muscle regeneration.
Nicola Bundschuh Lab manager	Primary muscle cell culture, reprogramming somatic cells into induced pluripotent stem cells, genome editing using CRISPR-Cas9, flow cytometry, FACS sorting.
Giada Bacchin PhD student	Direct reprogramming of somatic cells into myogenic progenitors, primary muscle/fibroblast cell culture and isolation, production of viral vectors, molecular cloning, human iPSCs, flow cytometry, biomaterials.
Veerle de Goederen PhD student	Muscle cell dedifferentiation, fish cell culture, transcriptomics
Christine Trautmann PhD student	Primary muscle cell isolation and cell culture of bovine myoblasts and muscle fibers
Ajda Lenardic PhD student	Gene editing and genetic engineering, cell biology with the focus on reprogramming of somatic cells into induced pluripotent stem cells and myogenic cells
Pjeter Gjonlleshaj PhD student	stem cell biology
Ali Kerem Kalkan PhD student	Human iPSCs and primary muscle cell culture, reprogramming human somatic cells into iPSCs, 3D muscle differentiation, Golden Gate cloning, transcriptional regulation using CRISPR-Cas nucleases, FACS sorting.

Lab. Prof. Perrine Castets

University of Geneva, Faculty of Medicine, Department Cell Physiology and Metabolism

Institute infrastructure: Microscopy, FACS, genomic platform, Proteomics facility, cell culture, muscle electroporation, AAV

Team	Personal expertise
Prof. Perrine Castets SNSF Assistant Professor	Muscle physiology; molecular biology; transgenic animal models; neuromuscular diseases; neuromuscular junction; autophagy
Dr. Alexandre Prola Maître Assistant	Molecular biology; metabolism; Muscle Stem Cells; mitochondria; Ca²⁺ flux
Florent Chabry Technicien	Mouse genotyping; immunohistochemistry; Signaling Pathway analysis
Loris Levet PhD student	Molecular biology; autophagy; autophagic vacuolar myopathies, histology
Ilaria Cocchiararo PhD student	Molecular biology; autophagy; autophagic vacuolar myopathies, histology

Lab Prof. Katrien De Bock

Exercise and Health lab, Department of Health Sciences and Technology, ETH Zurich

Lab infrastructure and techniques: (I) Freshly isolated cell culture: primary muscle cell culture, isolation of satellite cells, fibro-adipogenic progenitors, immune cells and muscle endothelial cells, (II) Muscle physiology and regeneration in vivo: intramuscular cell transplantation and graft analysis, skeletal muscle injury: cardiotoxin, glycerol and hind-limb ischemia, TSE running wheel system, indirect calorimetry analysis (Sable systems metabolic cages). (III) Relevant mouse strains: Pax7-mTmG. Mouse lines to study vascular biology in muscle.

Team	Personal expertise
Prof. Katrien De Bock	Metabolic reprogramming and crosstalk during muscle regeneration, exercise physiology, cell-cell interactions in skeletal muscle.
Dr. Inés Soro-Arnáiz PostDoc	Satellite cell isolation and culture, cardiotoxin-induced muscle injury, intramuscular satellite cell transplantation, immunofluorescent imaging and analysis of muscle tissue, flow cytometry

Lab Prof. Tobias Derfuss

University of Basel and University Hospital Basel

Lab infrastructure and techniques: Acetlycholine Receptor-specific, human-derived, monoclonal antibodies

Team	Personal expertise
Dr. Nicholas Sanderson group leader
Sebstian Holdermann PhD student

Lab Prof. Maud Frieden

University of Geneva, Department of Cell Physiology and Metabolism

Institute infrastructure: Calcium imaging, electrophysiology, human primary cell culture, lentivirus

Team	Personal expertise
Prof. Maud Frieden	Myogenesis and muscle regeneration, electrophysiology, Ca2+ imaging
Dr. Stephane Koenig scientific collaborator	Reserve cell activation, molecular biology, myogenesis and muscle regeneration, lentivirus, signal transduction
Dr. Tahir Idris PostDoc	Extracellular matrix, molecular biology, myotube maturation, signal transduction
Loann Laubry PhD student	Myoblast differentiation, Signal transduction, Ca2+ imaging, electrical stimulation on cell culture
Mélanie Fourgeaud PhD student	Reserve cell activation, genomic data analysis, molecular biology, signal transduction
Olivier Dupont Lab technician	Myoblast differentiation, Signal transduction, Ca2+ imaging

Lab Prof. Christoph Handschin

Biozentrum, University of Basel

Institute infrastructure: Treadmill (open and closed), voluntary wheel running, grip strength, CLAMS (comprehensive laboratory animal monitoring system), qNMR (body composition)

Team	Personal expertise
Prof. Christoph Handschin	Skeletal muscle cell plasticity in health and disease incl. exercise and muscle wasting pathologies
Dr. Regula Furrer Postdoc	Dysferlinopathy (in vivo testing, in situ force measurements

Lab Prof. Marisa Jaconi

University of Geneva, Faculty of Medicine, Department of Basic Neurosciences

Institute infrastructure: Cell culture and microscopy techniques; pre-GMP and GMP lab; muscle physiology; animal facility and analysis of muscle function

Team	Personal expertise
Prof. Marisa Jaconi	Human pluripotent stem cells (ESC and iPSC) and tissue-derived stem cells Cardiac and skeletal muscle differentiation Organoids and tissue engineering Cell therapy strategies and GMP cell production Setup for 3D sound-induced morphogenesis (Cymatix) Setups for microfluidics and electrophysiological characterization of organoids
Dr. Tania Rodrigues Post-Doc	Mesoangioblast biology, muscle differentiation and functional analysis, lentivector transduction and clonal selection GMP isolation and cell banking
Martha Iabel Gonzalez Duque PostDoc	Stem cells and cardiac valve reconstruction, 3D bioprinting, sound-induced morphogenesis

Lab Alexis Jourdain

Mitochondria & Energy Metabolism lab, Department of Biochemistry, University of Lausanne

Lab infrastructure and techniques: (I) Tissue culture: muscle, cancer and immune cell culture. (II) Systems biology: genome-wide CRISPR/Cas9 screening, nutrient screening, omics. (III) Mitochondrial biology: Respirometry, mtDNA expression, respiratory chain complexes assembly, mitochondrial disorders.

Team	Personal expertise
Prof. Alexis Jourdain	Mitochondria, systems biology
Sylvain Chollet biologist/lab manager
Emeline Recazens PostDoc	Mitochondria, muscle cell differentiation
Miriam Lisci PostDoc	Mitochondria, T cell immunometabolism
Mads Møller Foged PostDoc
Joan Blanco Fernandez PhD student	Mitochondria, macrophage immunometabolism
Abigail Lee Strefeler PhD student	Mitochondria, nutrient metabolismy
Marcell Harhai PhD student

Lab Prof. Didier Hannouche & Dr. Thomas Laumonier

Department of Orthopaedic Surgery, Faculty of Medicine & University Hospital, Geneva, Switzerland

Institute infrastructure: Hypoxic chamber, Whole Animal System for muscle physiology testing in mice, bioluminescence imaging.

Team	Personal expertise
Dr. Thomas Laumonier Senior scientist, PhD Co-responsible of the lab	Isolation of human myogenic stem cells, cell therapy, immunology, flow cytometry, gene therapy, bioluminescence imaging
Prof. Didier Hannouche Professor, MD Co-responsible of the lab	Orthopaedic surgery, cell therapy
Dr. Laure Gallay PostDoc	Animal microsurgery, PCR, histology
Axelle Bouche PhD student	Cell culture, flow cytometry, cell transplantation
Diego Michel Master student	Cell culture, flow cytometry, immunofluorescence
Dr. Axel Tollance PostDoc	Primary human cell culture, Flow cytometry, Seahorse

Lab Prof. Robert Katzschmann

Departement für Maschinenbau und Verfahrenstechnik, CLA Building, Laboratory of Soft Robotics, ETH Zurich

Institute infrastructure: 3D extrusion bioprinter, 3D printers, equipment for electrical stimulation of muscle cells and tissue

Team	Personal expertise
Robert Katzschmann Assistant Professor	Soft Robotics, Mechanical Engineering, Muscle Tissue Engineering, Electrical Stimulation of Muscle Cells and Tissue, Bio-hybrid Robots
Miriam Filippi Senior scientist	Muscle Tissue Engineering, Electrical Stimulation of Muscle Cells and Tissue, Biofabrication, 3D Extrusion Bioprinting, Bio-hybrid Robots
Oncay Yasa PostDoc	Soft Robotics, Mechanical Engineering, Muscle Tissue Engineering, Electrical Stimulation of Muscle Cells and Tissue, 3D Extrusion Bioprinting, Biomaterials, Bio-hybrid Robots
Lewis Jones PhD student	Cardiac and Skeletal Muscle Tissue Engineering, Volumetric 3D Bioprinting, Bio-hybrid Robots
Aiste Balciunaite PhD student
Asia Badolato PhD student
Manuel Mekkattu PhD student

Lab Prof. Peter Meister

Institute of Cell Bioogy, University of Bern

Institute infrastructure: Confocal Microscopy, Spinning Disk microscopy

Team	Personal expertise
P.D. Peter Meister	C. elegans, muscle differentiation, epigenetics, nuclear organization, microscopy
Karthik Mohanraj post-doc	Cell plasticity, muscle cell induction, pluripotency, genetic screens

Lab Prof. Nicolas Mermod

University of Lausanne, Biotechnology

Institute infrastructure: Muscle in situ electroporation, integrating and non-integrating non-viral DNA expression vectors, Next-generation DNA sequencing and genomics

Team	Personal expertise
Prof. Nicolas Mermod	Gene expression and regulation, genomics, epigenetic regulatory elements, non-viral vectors
Dr. Lionel Mavoungou Postdoctoral researcher	gene transfer in cultured muscle progenitor cells and transplantation, MDX murine model of Duchenne Muscular Dystrophy

Lab Prof. Matteo Moretti and Prof. Simone Bersini

Regenerative Medicine Technologies Lab, Ente Ospedaliero Cantonale (EOC), Bellinzona
Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano

Institute infrastructure
Human cell culture, in vitro modelling, biofabrication, organs-on-a-chip

Isolation and culture of primary cells from human musculo-skeletal biopsies (e.g. myoblasts, fibroblasts, mesenchymal stem cells)
Biofabrication of miniaturized in vitro models of the human skeletal muscle microenvironment embedding muscle fibers, endothelial cells and muscle-specific stromal cells
Biofabrication of human microvascular networks with applications in musculo-skeletal pathologies, oncology and aging

Technologies and techniques: Fused-deposition modelling 3D printer, Digital light processing 3D printer, Volumetric 3D bioprinter, Laser cutter, Plasma cleaner, High-vacuum pumps, Nitrogen gas generator, Nitrogen oven, Soft lithography, Electrical stimulation, Microfabrication, Microfluidics and organs-on-a-chip, Automated liquid handling, Confocal high-content imaging system, Biofabrication and Hydrogel patterning, Computational fluid dynamic simulations

Team	Personal expertise
Prof. Matteo Moretti	Tissue engineering, regenerative medicine for musculo-skeletal tissues (e.g. bone, muscle, cartilage, tendons), bioreactors, 3D printing
Prof. Simone Bersini	Muscle biofabrication, organ-specific vascularization, microfluidics, organs-on-a-chip for modeling cancer metastases and human aging
Stella Monestier PhD student	Bioprinting, microphysiological systems
Megi Ishmaku Research assistant	Primary cell isolation and culture, microfabrication
Giuseppe Talò Engineer	Design of electro-mechanical systems, computer-aided design, microfabrication, 3D printing, bioprinting
Marco Francese Master student	Computer-aided design, computational fluid dynamic simulations, microfabrication

Lab Prof. Markus A. Rüegg

University of Basel, Biozentrum

Institute infrastructure: AAV technology; mouse models; muscle force measurement; microscopy; Proteomics and RNA-seq analysis; FACS analysis; voluntary wheel running; CRISPR/Cas9

Team	Personal expertise
Prof. Markus A. Rüegg	Muscle physiology; molecular biology; transgenic animal models; neuromuscular diseases
Dr. Shuo Lin Research associate	Development of neuromuscular junctions; muscle growth and muscular dystrophies
Dr. Judith Reinhard Research associate	Molecular biology; biochemistry; histology; histochemistry; transgenic animal models; AAV-mediated gene therapy; muscular dystrophies (LAMA2 MD)
Dr. Daniel J. Ham Research associate	Muscle physiology; sarcopenia; muscle function testing
Dr. Ines Böhm Postdoc	Mammalian neuromuscular junctions, sarcopenia, cancer cachexia, method development, spatial transcriptomics, immunofluorescence, FDM 3D printing, microscopy + fluidics imaging, clinical trials (GCP), image analysis
Dr. Eleonora Maino PostDoc	Molecular biology, genome editing, disease modelling, neuromuscular disorders
Dr. Marco Thürkauf PostDoc	Molecular biology, muscle physiology, CRISPR/Cas9 technology, AAV preparation, omics data analysis
Dr. Alexander Ham PostDoc	Molecular biology, muscle physiology, NMJ physiology, sn/scRNAseq technology, omics data analysis
Timothy McGowan PhD student	Stem cells, muscle regeneration; muscular dystrophies (LAMA2 MD)
Julia Schedel PhD student	Myotendinous junction, muscular dystrophies (LAMA2 MD), molecular biology
Alexia Böck Pereda PhD student	Muscle biology, muscular dystrophies, molecular biology
Lena Jörin Technician	Genotyping of mice, lab management
Nicolas Lewerenz Master student	Primary myoblast culture, LAMA2 MD, AAV-mediated CRISPR/Cas9 delivery

Lab Dr. Francesco Santini and Prof. Oliver Bieri

Division of Radiological Physics, Department of Radiology, University Hospital Basel

Institute infrastructure: 1.5T and 3T human MRI scanners for in vivo imaging and spectroscopy, electronics laboratory, access to 31P coils for in vivo human spectroscopy and MR-compatible ergometer, equipment for electrical muscle stimulation during MRI.

Team	Personal expertise
Prof. Oliver Bieri Head of Radiological Physics	Methodological development, novel contrast mechanisms.
Dr. Francesco Santini Head of Muscle MRI	Methodological development, dynamic MRI; MRI safety; electronics design and development.
Dr. Xeni Deligianni PostDoc	Methodological development, quantitative and dynamic MR imaging and spectroscopy; MR image and data analysis.
Dr. Claudia Weidensteiner PostDoc	Methodological development, study design and data analysis, pediatric imaging.
Dr. Jakob Wasserthal PostDoc	Image analysis and Artificial Intelligence
Tanja Haas technician	MRI scanning
Philipp Madörin technician	MRI scanning

Lab Prof. Smita Saxena

University of Bern, Dept. for Biomedical research and Dept. of Neurology, Insespital

Institute infrastructure: Confocal microscopy, spinning disk microscopy for live and calcium imaging, muscle force measurement, cell culture, voluntary wheel running, rotarod, stereotaxic surgery, optogenetics, laser dissection microscopy, ALS rodent models (SOD1, TDP-43 and C9ORF72).

Team	Personal expertise
Prof. Smita Saxena	Degeneration of motor neruons and neuromuscular junctions in ALS, muscle factors that influence axonal regeneration status, mTOR signalling in motor neurons
Niran Maharjan Senior Researcher	Motor neuron and iPSC-derived neuronal cultures, electron microscopy
Mert Duman	sleep measurements
Federica Pilotto PhD student
Carla Pernaci PhD student
Rim Diab PhD student
Alexander Schmitz MD-PhD student

Lab Prof. Leonardo Scapozza

University of Geneva, Pharmaceutical Biochemistry

Institute infrastructure: Setup for measuring isometric force in sedated living mice or rats; Setup for measuring isometric and eccentric force in excised muscle; Setup for fluorescent imaging in living cells, mdx5Cv dystrophic mouse, mdx5Cv mice bearing conditional mutations for aromatase, estrogen receptors alpha and beta, cell culture facilities (P2 level), HTP plate readers, genomics platforms with capacity for RNA-sequencing and qPCR

Team	Personal expertise
Prof. Leonardo Scapozza	Biophysics of interactions: ITC, SPR, Thermophoresis, Enzymology Medicinal Chemistry: Cpds synthesis Biochemistry: protein expression (mg scale), protein purification, target-based in vitro assay, protein characterization (SEC, SEC-MALS)
Dr. Olivier Dorchies Senior Research Associate	Primary cultures of mouse skeletal muscle, in vivo force measurements, in vivo motor function (spontaneous locomotor activity, grid test, wheel running), Mouse models: mdx5Cv, FU-5Cv (muscle-specific, Dox-inducible, Flox-Utrophin mdx5Cv mouse), D2/5Cv (similar to D2.mdx, mdx5Cv allele in DBA/2J background). Influxes of radioactive calcium and sodium, fluorescent detection of ROS, roles of ROS and estrogen receptors in muscle dystrophy
Dr. Hesham Ismail Senior scientist	In vivo/ex vivo force measurements, primary mouse skeletal muscle cultures, fluorescent imaging of intracellular pH, sodium fluxes, calcium fluxes, ROS, roles of ROS in muscle dystrophy
Dr. Laurence Neff Research associate	Molecular biology, genome editing, viral vectors
Ghali Guedira PhD student	In vivo/Ex vivo force measurements, roles of ROS in muscle dystrophy.

Lab Profs. Michael Sinnreich, Susan Treves and Francesco Zorzato

University of Basel, Department Neurologie & Biomedizin

Institute infrastructure: Translational research on muscular dystrophies, Congenital myopathies with special focus on excitation contraction coupling dysregulation and calcium homeostasis.

Team	Personal expertise
Prof. Michael Sinnreich	Neuromuscular diseases Muscular Dystrophies
Prof. Susan Treves	Intracellular calcium measurements, resting membrane potential measurements with fluorescent dyes, Preparation of primary muscle moytube cultures (human, mouse, EOM) Western blots, preparation of poly and monoclonal Abs, protein purification
Prof. Francesco Zorzato	Force measurements on fast and slow twitch muscles, Ca2+ imaging on single muscle fibers, single fiber dissection, SPARK analysis, electroporation. Western blots, preparation of Abs, protein purification
Dr. Jochen Kinter PostDoc	Experience in NGS, drug screenings, aptamers
Dr. Lionel Tintignac senior scientist	Myogenesis, primary culture of muscle cells, NGS and Ribo-seq, proteomics and PTM. Proximity labeling
Dr. Christian Klingler PostDoc	Experience in NGS, drug screenings, aptamers
Dr. Alexis Ruiz PostDoc	Force measurements on fast and slow twitch muscles. Single fiber dissection and Ca2+ imaging on single muscle fibers. Confocal microscopy, Western blots, qPCR. In vivo assessment of mouse muscle force
Sofia Benucci PhD student	Force measurements on fast, slow twitch muscles and EOM muscles. Histology of muscle sections. Ca²⁺ imaging on single muscle fibers and single cells, qPCR, confocal microscopy, western blotting. In vivo assessment of mouse muscle force
Yusuf Ertuna PostDoc	Myogenesis, primary culture of muscle cells, proteomic and PTM. Proximity labeling
Huiying Li PhD student	FACS sorting, cytokine profiling, EBV cells, immunocharacterisation
Wen Jin MD, PhD student	Characterisation cell lines from patients carrying RyR1 mutations
Kenshiro Kido MD	Malignat Hyperthermia myotubes
Iren Cerem Master student	EBV cells characterisation
Hervé Meier Research Assistant (Master’s)	Western blots, qPCR, protein purification, cell and tissue culture, subcellular fractionation, calcium imaging and confocal Microscopy, pPCR and Western blotting
Raphael Schmid Master Student	DUX4 Biogenesis, Ubiquitination, Protein Homeostatis
Adeline Stiefvater Research technician	Mouse muscle dissection, primary muscle cell and fiber culture, drug screening. EX vivo myotonia measurements

Lab Prof. Patrick Tschopp

Laboratory of Regulatory Evolution, DUW Zoology, University of Basel

Institute infrastructure and techniques: (I) single-cell genomics: in-house production and bioinformatics analyses of single-cell genomics data sets, namely 10x Genomics scRNA-seq, snRNA-seq and scATAC-seq, as well as SMART-seq2 scRNA-seq (II) lightsheet microscopy: whole-mount immunohistochemistry, lightsheet microscopy and image analysis (III) Axonal backfills: muscle-specific axonal backfills and single-cell motor neuron picking in developing chicken embryos

Team	Personal expertise
Prof. Patrick Tschopp PI	Developmental biology and evolutionary-comparative developmental biology, transcriptional regulation, functional genomics and single-cell functional genomics, experimental embryology
Dr. Maëva Luxey Senior Research Associate	Developmental neurobiology, primary cell culture, axon guidance, axonal backfilling, muscle microdissection, functional genomics and single cell functional genomics, lightsheet and confocal microscopy, experimental embryology
Fabio Sacher PhD student	Analysis of 10X and SMART-seq2 scRNA-seq data, DE testing, and data visualisation in R.

Lab Dr. Bernhard Wehrle-Haller

University of Geneva, School of medicine

Institute infrastructure: Microscopy, live-cell imaging, cell culture, fluorescent proteins

Team	Personal expertise
Dr. Bernhard Wehrle-Haller PD, PA	Dynamic regulation of cell-matrix adhesions, live cell imaging, cell culture, FRAP, microscopy, live imaging
Michael Bachmann PostDoc	Fluorescent tag-proteins, live imaging, FRAP, integrin signaling, surface patterning
Jérémy Kessler PhD student

Lab Prof. Werner Z'Graggen

Inselspital Bern, Department of Neurology

Institute infrastructure: equipment for muscle and nerve excitability measurements, ENMG equipment, muscle MR imaging, histology, mitochondrial activity essays

Team	Personal expertise
Prof. Hugh Bostock PhD, researcher	Musle and nerve excitability measurements
Belén Rodriguez PostDoc	Muscle and nerve excitability measurements