Actualités

Transcriptional network analysis in muscle reveals AP-1 as a partner of PGC-1α in the regulation of the hypoxic gene program.

Baresic M, Salatino S, Kupr B, van Nimwegen E, Handschin C. Mol Cell Biol. 2014 Jun 9.

09 juin 2014


Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation.

Moursy A, Allain FH, Cléry A. Nucleic Acids Res. 2014 Apr 1.

07 avril 2014


Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1α.

Arnold AS, Gill J, Christe M, Ruiz R, McGuirk S, St-Pierre J, Tabares L, Handschin C. Nat Commun. 2014 Apr 1;5:3569.

02 avril 2014


Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases.

Svensson K, Handschin C. Drug Discov Today. 2014 Mar 12. Review

19 mars 2014


Molecular targets to treat muscular dystrophies.

Kinter J, Sinnreich M. Swiss Med Wkly. 2014 Feb 19.

24 février 2014


Injection of a Soluble Fragment of Neural Agrin (NT-1654) Considerably Improves the Muscle Pathology Caused by the Disassembly of the Neuromuscular Junction.

Hettwer S, Lin S, Kucsera S, Haubitz M, Oliveri F, Fariello RG, Ruegg MA, Vrijbloed JW. PLoS One. 2014 Feb 10;9(2)

24 février 2014


The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling.

Pérez-Schindler J, Summermatter S, Santos G, Zorzato F, Handschin C. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20314-9.

20 décembre 2013