News

Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns.

Pérez-Berlanga M, Wiersma VI, Zbinden A, De Vos L, Wagner U, Foglieni C, Mallona I, Betz KM, Cléry A, Weber J, Guo Z, Rigort R, de Rossi P, Manglunia R, Tantardini E,...

04 September 2023


SPTLC1 p.Leu38Arg, a novel mutation associated with childhood ALS.

Lone MA, Zeng S, Bourquin F, Wang M, Huang S, Lin Z, Tang B, Zhang R, Hornemann T. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Sep;1868(9):159359.

01 September 2023


Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells.

Qabrati X, Kim I, Ghosh A, Bundschuh N, Noé F, Palmer AS, Bar-Nur O. NPJ Regen Med. 2023 Aug 8;8(1):43.

08 August 2023


Guideline "Motor neuron diseases" of the German Society of Neurology (Deutsche Gesellschaft für Neurologie).

Petri S, Grehl T, Grosskreutz J, Hecht M, Hermann A, Jesse S, Lingor P, Löscher W, Maier A, Schoser B, Weber M, Ludolph AC. Neurol Res Pract. 2023 Jun 15;5(1):25.

15 Juni 2023


The mitochondrial calcium uniporter (MCU) activates mitochondrial respiration and enhances mobility by regulating mitochondrial redox state.

Weiser A, Hermant A, Bermont F, Sizzano F, Karaz S, Alvarez-Illera P, Santo-Domingo J, Sorrentino V, Feige JN, De Marchi U. Redox Biol. 2023 Jun 4;64:102759.

04 Juni 2023


Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging.

Lima TI, Laurila PP, Wohlwend M, Morel JD, Goeminne LJE, Li H, Romani M, Li X, Oh CM, Park D, Rodríguez-López S, Ivanisevic J, Gallart-Ayala H, Crisol B, Delort F,...

17 Mai 2023


ConFERMing the role of talin in integrin activation and mechanosignaling.

Bachmann M, Su B, Rahikainen R, Hytönen VP, Wu J, Wehrle-Haller B. J Cell Sci. 2023 Apr 15;136(8):jcs260576.

15 April 2023


Nerve pathology is prevented by linker proteins in mouse models for LAMA2-related muscular dystrophy.

Reinhard JR, Porrello E, Lin S, Pelczar P, Previtali SC, Rüegg MA. PNAS Nexus. 2023 Mar 15;2(4):pgad083.

01 April 2023


CERT1 mutations perturb human development by disrupting sphingolipid homeostasis.

Gehin C, Lone MA, Lee W, Capolupo L, et. al. J Clin Invest. 2023 Mar 28:e165019.

28 März 2023