News

Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia.

Börsch A, Ham DJ, Mittal N, Tintignac LA, Migliavacca E, Feige JN, Rüegg MA, Zavolan M. Commun Biol. 2021 Feb 12;4(1):194.

15 Februar 2021


NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle.

Romani M, Sorrentino V, Oh CM, Li H, de Lima TI, Zhang H, Shong M, Auwerx J. Cell Rep. 2021 Jan 19;34(3):108660.

29 Januar 2021


Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing.

Cléry A, Krepl M, Nguyen CKX, Moursy A, Jorjani H, Katsantoni M, Okoniewski M, Mittal N, Zavolan M, Sponer J, Allain FH. Nat Commun. 2021 Jan 18;12(1):428.

18 Januar 2021


Texture analysis and machine learning to predict water T2 and fat fraction from non-quantitative MRI of thigh muscles in Facioscapulohumeral muscular dystrophy.

Felisaz PF, Colelli G, Ballante E, Solazzo F, Paoletti M, Germani G, Santini F, Deligianni X, Bergsland N, Monforte M, Tasca G, Ricci E, Bastianello S, Figini S,...

15 Januar 2021


Targeting Nrf2 for the treatment of Duchenne Muscular Dystrophy.

Kourakis S, Timpani CA, de Haan JB, Gueven N, Fischer D, Rybalka E. Redox Biol. 2021 Jan;38:101803

04 Januar 2021


Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding.

Zhang P, Azizi L, Kukkurainen S, Gao T, Baikoghli M, Jacquier MC, Sun Y, Määttä JAE, Cheng RH, Wehrle-Haller B, Hytönen VP, Wu J. Proc Natl Acad Sci U S A. 2020

07 Dezember 2020


Dynamic MRI of plantar flexion: A comprehensive repeatability study of electrical stimulation-gated muscle contraction standardized on evoked force.

Deligianni X, Hirschmann A, Place N, Bieri O, Santini F. PLoS One. 2020 Nov 5;15(11):e0241832.

30 November 2020


Macrophage-derived glutamine boosts satellite cells and muscle regeneration.

Shang M, Cappellesso F, Amorim R, Serneels J, Virga F, Eelen G, Carobbio S, Rincon MY, Maechler P, De Bock K, Ho PC, Sandri M, Ghesquière B, Carmeliet P, Di Matteo M,...

16 November 2020


Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs.

Nguyen L, Laboissonniere LA, Guo S, Pilotto F, Scheidegger O, Oestmann A, Hammond JW, Li H, Hyysalo A, Peltola R, Pattamatta A, Zu T, Voutilainen MH, Gelbard HA, Saxena...

30 Oktober 2020


The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering.

Kukkurainen S, Azizi L, Zhang P, Jacquier MC, Baikoghli M, von Essen M, Tuukkanen A, Laitaoja M, Liu X, Rahikainen R, Orłowski A, Jänis J, Määttä JAE, Varjosalo M,...

12 Oktober 2020