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The potential and benefits of repurposing existing drugs to treat rare muscular dystrophies

Hesham M. Ismail, Olivier M. Dorchies & Leonardo Scapozza Expert Opinion on Orphan Drugs, DOI: 10.1080/21678707.2018.1452733

27 März 2018


Autologous Cell Therapy Approach for Duchenne Muscular Dystrophy using PiggyBac Transposons and Mesoangioblasts.

Iyer PS, Mavoungou LO, Ronzoni F, Zemla J, Schmid-Siegert E, Antonini S, Neff LA, Dorchies OM, Jaconi M, Lekka M, Messina G, Mermod N. Mol Ther. 2018 Feb 2 pii:...

13 März 2018


Congenital myopathies: disorders of excitation-contraction coupling and muscle contraction.

Jungbluth H, Treves S, Zorzato F, Sarkozy A, Ochala J, Sewry C, Phadke R, Gautel M, Muntoni F. Nat Rev Neurol. 2018 Mar;14(3):151-167.

01 März 2018


Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy.

Boido M, De Amicis E, Valsecchi V, Trevisan M, Ala U, Ruegg MA, Hettwer S, Vercelli A. Front Cell Neurosci. 2018 Jan 30;12:17.

31 Januar 2018


Over-expression of a retinol dehydrogenase (SRP35/DHRS7C) in skeletal muscle activates mTORC2, enhances glucose metabolism and muscle performance.

Ruiz A, Dror E, Handschin C, Furrer R, Perez-Schindler J, Bachmann C, Treves S, Zorzato F. Sci Rep. 2018 Jan 12;8(1)

15 Januar 2018


Plasticity of the Muscle Stem Cell Microenvironment

Dinulovic I, Furrer R, Handschin C. Adv Exp Med Biol. 2017;1041:141-169

05 Januar 2018


Short vs. long pulses for testing knee extensor neuromuscular properties: does it matter?

Giroux C, Roduit B, Rodriguez-Falces J, Duchateau J, Maffiuletti NA, Place N. Eur J Appl Physiol. 2017 Dec 7

11 Dezember 2017


Laminin-deficient muscular dystrophy: Molecular pathogenesis and structural repair strategies.

Yurchenco PD, McKee KK, Reinhard JR, Rüegg MA. Matrix Biol. 2017 Nov 27.

27 November 2017


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