News

PGC-1α plays a pivotal role in simvastatin-induced exercise impairment in mice.

Panajatovic MV, Singh F, Roos NJ, Duthaler U, Handschin C, Krähenbühl S, Bouitbir J. Acta Physiol (Oxf). 2019 Oct 12.

12 Oktober 2019


Connective tissue fibroblasts from highly regenerative mammals are refractory to ROS-induced cellular senescence.

Saxena S, Vekaria H, Sullivan PG, Seifert AW. Nat Commun. 2019 Sep 27;10(1):4400.

27 September 2019


Adipogenic progenitors keep muscle stem cells young.

Ancel S, Mashinchian O, Feige JN. Aging (Albany NY). 2019 Sep 19

19 September 2019


BDNF is a mediator of glycolytic fiber-type specification in mouse skeletal muscle.

Delezie J, Weihrauch M, Maier G, Tejero R, Ham DJ, Gill JF, Karrer-Cardel B, Rüegg MA, Tabares L, Handschin C. Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):16111-16120.

06 August 2019


mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4.

Castets P, Rion N, Théodore M, Falcetta D, Lin S, Reischl M, Wild F, Guérard L, Eickhorst C, Brockhoff M, Guridi M, Ibebunjo C, Cruz J, Sinnreich M, Rudolf R, Glass DJ,...

18 Juli 2019


Extraocular muscle function is impaired in ryr3 -/- mice.

Eckhardt J, Bachmann C, Sekulic-Jablanovic M, Enzmann V, Park KH, Ma J, Takeshima H, Zorzato F, Treves S. J Gen Physiol. 2019 Jul 1;151(7):929-943

02 Juli 2019


Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance.

Agudelo LZ, Ferreira DMS, Dadvar S, Cervenka I, Ketscher L, Izadi M, Zhengye L, Furrer R, Handschin C, Venckunas T, Brazaitis M, Kamandulis S, Lanner JT, Ruas JL. Nat...

24 Juni 2019


Structural Transition, Function and Dysfunction of TDP-43 in Neurodegenerative Diseases.

Afroz T, Pérez-Berlanga M, Polymenidou M. Chimia (Aarau). 2019 May 29;73(6):380-390.

01 Juni 2019


Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA.

Donadon I, Bussani E, Riccardi F, Licastro D, Romano G, Pianigiani G, Pinotti M, Kostantinova P, Evers M, Lin S, Rüegg MA, Pagani F. Nucleic Acids Res. 2019 May 25....

31 Mai 2019


Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.

Lukjanenko L, Karaz S, Stuelsatz P, Gurriaran-Rodriguez U, Michaud J, Dammone G, Sizzano F, Mashinchian O, Ancel S, Migliavacca E, Liot S, Jacot G, Metairon S, Raymond...

30 Mai 2019


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